神经元的轴突的生长发育是一个复杂的过程。由于这一过程牵涉到复杂的生化和细胞反应,并且与诸多神经疾病的起源密切相关,所以是当前神经科学界的主要研究对象之一。
但就在今天,一项发表于《自然-神经科学》的最新研究试图改写人们对轴突形态的根本认知。来自约翰·霍普金斯大学医学院与加州大学圣地亚哥分校的研究团队在显微图像中发现,哺乳动物的轴突是由一个个形似珍珠的囊泡均匀地串联而成,就像是一根纳米级的珍珠手链!一个更具颠覆性的观点是,这些“珍珠”可能还会影响动作电位的传导速度。
· 动作电位的传导:当树突和胞体整合的信号达到阈值时,轴突起始段(轴丘)会触发动作电位,并沿轴突快速传导。
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